IDH1 inhibitor ยท small molecule
IDH305
1 active trials, targeting IDH1. Not approved for any biomarker on marked.bio yet.
Counts only trials that select patients by one of the biomarkers on marked.bio, not every trial of this drug.
Biomarkers
| Biomarker | Active trials | All trials | Furthest active phase |
|---|---|---|---|
| IDH1/2 mutation | 1 | 3 | Phase 1 |
Sponsors
Industry sponsors leading active biomarker-selected trials of IDH305.
- Novartis 1
Trials
1 of 3 trials shown
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A Study of IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations
Documented IDH1R132-mutant tumors
IDH1/2 mutationAdvanced Malignancies That Harbor IDHR132 Mutations
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Trial of IDH305 in IDH1 Mutant Grade II or III Glioma
Patients must have written documentation of IDH1 mutation at the R132 locus by immunohistochemistry or DNA sequencing in their tumor.
IDH1/2 mutationGlioma
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A Dose Finding Study of IDH305 With Standard of Care in IDH1 Mutant Acute Myeloid Leukemia
Documentation of IDH1R132 mutation of tumor
IDH1/2 mutationAcute Myeloid Leukemia (AML)
No trials match these filters.