FGFR inhibitor · small molecule
gunagratinib
1 active trials across 2 of our biomarkers, targeting FGFR1-4. Not approved for any biomarker on marked.bio yet.
Also known as ICP-192.
Counts only trials that select patients by one of the biomarkers on marked.bio, not every trial of this drug.
Biomarkers
| Biomarker | Active trials | All trials | Furthest active phase |
|---|---|---|---|
| FGFR2 fusion or rearrangement | 1 | 5 | Phase 2 |
| FGFR3 alteration (mutation or fusion) | 0 | 3 | – |
Sponsors
Industry sponsors leading active biomarker-selected trials of gunagratinib.
- Beijing InnoCare Pharma Tech 1
Trials
1 of 5 trials shown
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A Study of ICP-192 in Patients With FGFR2-Rearranged Unresectable or Metastatic Intrahepatic Cholangiocarcinoma
FGFR2 fusion /rearrangement as confirmed by the central laboratory.
FGFR2 fusion or rearrangementStatus may be outdated, last updated 2024-02-07Intrahepatic Cholangiocarcinoma (ICC)
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A Clinical Trial of ICP-192 in Treated Patients With Advanced Solid Tumors With FGF/FGFR Gene Alterations
…atients with HNC cancer who have failed or cannot tolerate standard therapy, and with FGF/FGFR gene alteration
FGFR3 alteration (mutation or fusion)FGFR2 fusion or rearrangementAdvanced Solid Tumor
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A Study of ICP-192 in Patients With Advanced Solid Tumors
Phase II: Existing test reports have confirmed the FGFR gene alteration or the central laboratory has detected the FGFR gene alteration.
FGFR3 alteration (mutation or fusion)FGFR2 fusion or rearrangementAdvanced Solid Tumors, Urothelial Carcinoma, Cholangiocarcinoma
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An Efficacy and Safety Study of ICP-192 in Subjects With Bladder Urothelial Cancer
…192 in Subjects With Surgically Unresectable or Metastatic Bladder Urothelial Cancer With FGFR Genetic Aberrations.
FGFR3 alteration (mutation or fusion)FGFR2 fusion or rearrangementBladder Urothelial Cancer
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Clinical Study of ICP-192 in Solid Tumors Patients
FGFR2 translocation/fusion has been reported or FGFR2 translocation/fusion has been detected in central labor…
FGFR2 fusion or rearrangementSolid Tumor
No trials match these filters.