CBP/β-catenin inhibitor · small molecule

E7386

1 active trials, targeting CBP/β-catenin. Not approved for any biomarker on marked.bio yet.

Counts only trials that select patients by one of the biomarkers on marked.bio, not every trial of this drug.

Biomarkers

BiomarkerActive trialsAll trialsFurthest active phase
MSI-H / dMMR 1 1 Phase 1/2

Sponsors

Industry sponsors leading active biomarker-selected trials of E7386.

  1. Eisai 1

Trials

Status

1 of 1 trials shown

  1. A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor

    Active, not recruiting Phase 1/2 Eisai Started 2019Primary completion 2027-03 NCT04008797

    E7386lenvatinibdoxorubicinpaclitaxel

    Immune checkpoint inhibitor for participants with microsatellite instability-high (MSI-H) CRC

    MSI-H / dMMREndometrial Neoplasms, Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms