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<title>marked.bio: what&#x27;s new</title><link>https://marked.bio/new/index.html</link>
<description>Weekly changes across biomarker-selected cancer trials and approvals.</description><language>en</language>
<item><title>Week to 27 October 2026: 5 new trials</title><link>https://marked.bio/new/index.html#w-2026-10-27</link><guid isPermaLink="false">marked.bio-week-2026-10-27</guid><pubDate>Tue, 27 Oct 2026 12:00:00 +0000</pubDate><description>&lt;p&gt;&lt;b&gt;5 new trials&lt;/b&gt; on marked.bio between 20 October 2026 and 27 October 2026.&lt;/p&gt;&lt;h3&gt;New trials (5)&lt;/h3&gt;&lt;ul&gt;&lt;li&gt;&lt;a href=&quot;https://clinicaltrials.gov/study/NCT07897188&quot;&gt;ASKC202 Plus Limertinib as the First-line Therapy for Patients With EGFRm+/MET+ Locally Advanced or Metastatic NSCLC&lt;/a&gt; (Phase 3, Jiangsu Aosaikang Pharmaceutical) &lt;i&gt;EGFR exon 19 deletion / L858R&lt;/i&gt;&lt;/li&gt;&lt;li&gt;&lt;a href=&quot;https://clinicaltrials.gov/study/NCT07886905&quot;&gt;Pulsed Stereotactic Ablative Radiotherapy (PULSAR) With Systematic Therapy for Thyroid Cancer&lt;/a&gt; (Phase 2, Washington University School of Medicine) &lt;i&gt;BRAF V600E&lt;/i&gt;&lt;/li&gt;&lt;li&gt;&lt;a href=&quot;https://clinicaltrials.gov/study/NCT07897721&quot;&gt;A Study to Learn About the Study Medicine Called PF-08165784 in People With PIK3CA-Mutated Advanced or Metastatic Solid Tumors&lt;/a&gt; (Phase 1, Pfizer) &lt;i&gt;PIK3CA activating mutation&lt;/i&gt;&lt;/li&gt;&lt;li&gt;&lt;a href=&quot;https://clinicaltrials.gov/study/NCT07888647&quot;&gt;IDH1-vac in Patients With Newly Diagnosed IDH1R132H-positive High-grade Astrocytomas&lt;/a&gt; (Phase 2, German Cancer Research Center) &lt;i&gt;IDH1/2 mutation&lt;/i&gt;&lt;/li&gt;&lt;li&gt;&lt;a href=&quot;https://clinicaltrials.gov/study/NCT07891468&quot;&gt;huCART19-IL18-CD428z Cells for the Treatment of Patients With HIV With CD19+ Cancers&lt;/a&gt; (Phase 1, University of Pennsylvania) &lt;i&gt;ALK fusion&lt;/i&gt;&lt;/li&gt;&lt;/ul&gt;&lt;p&gt;Plus 3 trials open to a broader group (for example any KRAS mutation), listed on &lt;a href=&quot;https://marked.bio/new/index.html&quot;&gt;What&#x27;s new&lt;/a&gt;.&lt;/p&gt;</description></item>
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